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            VEGF Rabbit pAb
            
                    EA320
                    
            
                        
            
                            
            
                                規(guī)格：
                                價(jià)格：
                            
            
                                                        
            
                                50μL
                                ￥1280.00
                            
            
                                                        
            
                                100μL
                                ￥1980.00
                            
            
                                                    
            
                    
            
                    
                
            
            
            
        
            

                
            
            
            
                
            Overview
                    文獻(xiàn)
            
                
            
                    
            
                        
            
                            
            
                                
            
                                    
            
                                        Product name:
                                        VEGF Rabbit pAb
                                    
            
                                                                            
            
                                            Reactivity:
                                            Human, Rat, Mouse
                                        
            
                                                                                
            
                                            Alternative Names:
                                            VEGFA antibody, VPF antibody, VEGF120 antibody, Vascular endothelial growth factor antibody
                                        
            
                                                                                
            
                                           Source:
                                           Rabbit
                                           
                                        
            
                                                                                
            
                                           Dilutions:
                                           IHC 1:200-500
                                           
                                        
            
                                                                                
            
                                           Immunogen:
                                           Recombinant Protein
                                           
                                        
            
                                                                                
            
                                           Storage:
                                           PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid?repeated?freeze-thaw?cycles.
                                           
                                        
            
                                                                                
            
                                           Clonality:
                                           Polyclonal
                                           
                                        
            
                                                                                
            
                                           Isotype:
                                           IgG
                                           
                                        
            
                                                                                
            
                                           Concentration:
                                           1mg/mL
                                           
                                        
            
                                                                                
            
                                           Observed Band:
                                           23,45kDa
                                           
                                        
            
                                                                                
            
                                           GeneID:
                                           7422
                                           
                                        
            
                                                                                
            
                                           Human Swiss-Prot No:
                                           P15692
                                           
                                        
            
                                                                                
            
                                           Cellular localization:
                                           Secreted
                                           
                                        
            
                                                                                
            
                                           Background:
                                           VEGFA, also named as VEGF or VPF, belongs to the PDGF/VEGF growth factor family. It is a growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. VEGFA induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. It binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. Defects in VEGFA are associated with microvascular complications of diabetes type 1 (MVCD1). VEGFA has 17 isoforms with MW from 16 to 45 kDa. Some isoforms have homodimer forms (e.g.; VEGFA189 38kDa or VEFGA110 34kDa). VEGF-A exists in at least seven homodimeric isoforms. The monomers consist of 121, 145, 148, 165, 183, 189, or 206 amino acids (PMID:15602010 ). This antibody can recognize all VEGFA isoforms.
                                           
                                        
            
                                                                        
            
                            
            
                                                        
                                                    
            
                    
            
                
            
            
            
                        
                    
            
    
            
    




            
    
            
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