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            CD5 Mouse mAb
            EM1071
            規(guī)格: 價格:
            50μL ¥1280.00
            100μL ¥1980.00

            Overview

            Product name: CD5 Mouse mAb
            Reactivity: Human, Rat, Mouse
            Alternative Names: CD5 molecule, LEU1, Lymphocyte antigen T1/Leu 1, T1
            Source: Mouse
            Dilutions: IHC 1:100-200
            Immunogen: Synthetic Peptide
            Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid?repeated?freeze-thaw?cycles.
            Clonality: Monoclonal
            Isotype: IgG1
            Concentration: 1mg/mL
            GeneID: 921
            Human Swiss-Prot No: P06127
            Cellular localization: Membrane
            Background: CD5 is a cluster of differentiation found on a subset of IgM-secreting B cells called B-1 cells, and also on T cells. B-1 cells have limited diversity of their B-cell receptor due to their lack of the enzyme terminal deoxynucleotidyl transferase (TdT) and are potentially self-reactive. CD5 serves to mitigate activating signals from the BCR so that the B-1 cells can only be activated by very strong stimuli (such as bacterial proteins) and not by normal tissue proteins.
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