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            eIF4A1 Mouse mAb
            
                    EM1136
                    
            
                        
            
                            
            
                                規(guī)格：
                                價格：
                            
            
                                                        
            
                                50μL
                                ￥1280.00
                            
            
                                                        
            
                                100μL
                                ￥1980.00
                            
            
                                                    
            
                    
            
                    
                
            
            
            
        
            

                
            
            
            
                
            Overview
                    
            
                
            
                    
            
                        
            
                            
            
                                
            
                                    
            
                                        Product name:
                                        eIF4A1 Mouse mAb
                                    
            
                                                                            
            
                                            Reactivity:
                                            Human, Rat, Mouse
                                        
            
                                                                                
            
                                            Alternative Names:
                                            DDX2, eIF 4A I, Eukaryotic initiation factor 4A-1, ATP-dependent RNA helicase eIF4A-1,DDX2A
                                        
            
                                                                                
            
                                           Source:
                                           Mouse
                                           
                                        
            
                                                                                
            
                                           Dilutions:
                                           WB 1:1,000-3,000 IF 1:100-200? IHC 1:100-200
                                           
                                        
            
                                                                                
            
                                           Immunogen:
                                           Synthetic Peptide
                                           
                                        
            
                                                                                
            
                                           Storage:
                                           PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid?repeated?freeze-thaw?cycles.
                                           
                                        
            
                                                                                
            
                                           Clonality:
                                           Monoclonal
                                           
                                        
            
                                                                                
            
                                           Isotype:
                                           IgG1
                                           
                                        
            
                                                                                
            
                                           Concentration:
                                           1mg/mL
                                           
                                        
            
                                                                                
            
                                           Observed Band:
                                           48kDa
                                           
                                        
            
                                                                                
            
                                           GeneID:
                                           1973
                                           
                                        
            
                                                                                
            
                                           Human Swiss-Prot No:
                                           P60842
                                           
                                        
            
                                                                                
            
                                           Cellular localization:
                                           Cytosol,Extracellular region or secreted
                                           
                                        
            
                                                                                
            
                                           Background:
                                           The eukaryotic initiation factor-4A (eIF4A) family consists of 3 closely related proteins EIF4A1, EIF4A2, and EIF4A3. These factors are required for the binding of mRNA to 40S ribosomal subunits. Eukaryotic initiation factor (eIF) complex 2 forms a ternary complex with GTP and the initiator Met-tRNA – this process is regulated by guanine nucleotide exchange and phosphorylation and serves as the main regulatory element of the bottleneck of protein expression.
                                           
                                        
            
                                                                        
            
                            
            
                                                    
            
                    
            
                
            
            
            
                        
                    
            
    
            
    




            
    
            
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