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            a-actinin (4A12) Mouse mAb
            EM1261
            規(guī)格: 價(jià)格:
            50μL ¥1280.00
            100μL ¥1980.00

            Overview

            Product name: a-actinin (4A12) Mouse mAb
            Reactivity: Human, Rat, Mouse
            Alternative Names: actinin 1 smooth muscle antibody, actinin alpha 1 antibody, ACTN 1 antibody, FLJ40884 antibody
            Source: Mouse
            Dilutions: IHC 1:100-200
            Immunogen: Recombinant Protein
            Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid?repeated?freeze-thaw?cycles.
            Clonality: Monoclonal
            Isotype: IgG1
            Concentration: 1mg/mL
            Observed Band: 103kDa
            GeneID: 87
            Human Swiss-Prot No: P12814
            Cellular localization: Cell junction,?Cell membrane,?Cell projection,?Cytoplasm,?Cytoskeleton,?Membrane
            Background: α-Actinin belongs to the spectrin family of cytoskeletal proteins. α-Actinin is necessary for the attachment of actin filaments to the Z-lines in skeletal muscle cells, and to the dense bodies in smooth muscle cells. The functional protein is an anti-parallel dimer, which cross-links the thin filaments in adjacent sarcomeres, and therefore coordinated contractions between sarcomeres in the horizontal axis.
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