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產(chǎn)品中心

TRIpure總RNA提取試劑（同Trizol）

EP013

規(guī)格：	價(jià)格：
100mL	￥500.00
250mL	￥1000.00

下載說明 ①

Overview 文獻(xiàn)

Product name:	TRIpure Total RNA Extraction Reagent（As Trizol）
產(chǎn)品介紹:	TRIpure?Total RNA Extraction Reagent?是一種用于各種動(dòng)植物、細(xì)菌組織/細(xì)胞總RNA抽提的試劑，具有極強(qiáng)的裂解能力，可在短時(shí)間內(nèi)裂解細(xì)胞和組織樣本，保持樣品中RNA的完整性，有效抑制RNA的降解。樣品在該試劑中能夠充分被裂解，在加入氯仿離心后，溶液會(huì)形成上清層、中間層和有機(jī)層?(鮮紅色下層)，RNA分布在上層水相中，收集上清層后，經(jīng)異丙醇沉淀便可回收得到Total RNA。提取的總RNA純度高，基本不含蛋白質(zhì)及基因組DNA，?可直接用于Northern、點(diǎn)雜交、mRNA純化、體外翻譯、RT-PCR、poly(A)+選擇、RNA酶保護(hù)分析以及構(gòu)建cDNA文庫等多種分子生物學(xué)實(shí)驗(yàn)。
產(chǎn)品特點(diǎn):	提取質(zhì)量高：可在1 h 內(nèi)提取得率高、純度高、完整性好的總RNA 添加指示劑：添加了特殊指示劑，離心分層后下層為粉紅色，便于吸取上清靈敏度高：對(duì)病毒等微量樣本的提取具有更高的提取效率樣品處理量靈活：對(duì)少量的組織(50-100mg)和細(xì)胞(5×10^6)以及大量的組織(≥1g)和細(xì)胞(>10^7)均有較好的裂解效果。

BIOMEDICINE & PHARMACOTHERAPY

Metformin ameliorates olanzapine-induced insulin resistance via suppressing macrophage infiltration and inflammatory responses in rats

日期：2021-10-20 IF：4.8
International Journal of Medical Sciences

Left Stellate Ganglion Ablation Inhibits Ventricular Arrhythmias through Macrophage Regulation in Canines with Acute Ischemic Stroke

日期：2021-10-20 IF：2.557
Frontiers in Pharmacology

Fusobacterium nucleatum activates endoplasmic reticulum stress to promote crohn's disease development via the upregulation of CARD3 expression

日期：2021-10-26 IF：4.225
Frontiers in Oncology

The Optimal Outcome of Suppressing Ewing Sarcoma Growth in vivo With Biocompatible Bioengineered miR-34a-5p Prodrug

日期：2021-10-26 IF：4.848
Biology of Reproduction

Par3/integrin β1 regulates embryo adhesion via changing endometrial luminal epithelium polarity

日期：2021-10-26 IF：3.206
Cellular and Molecular Neurobiology

Sevoflurane Induces Learning and Memory Impairment in Young Mice Through a Reduction in Neuronal Glucose Transporter 3

日期：2021-10-26 IF：3.464
Frontiers in Pharmacology

Endoplasmic Reticulum Stress to Promote Crohn's Disease Development via the Upregulation of CARD3 Expression

日期：2021-10-26 IF：-
International Journal of Medical Sciences

Left Stellate Ganglion Ablation Inhibits Ventricular Arrhythmias through Macrophage Regulation in Canines with Acute Ischemic Stroke

日期：2021-10-26 IF：2.557
Aging

Hsa_circ_0044226 knockdown attenuates progression of pulmonary fibrosis by inhibiting CDC27

日期：2021-10-26 IF：-
Experimental and Therapeutic Medicine

Analysis of piRNA expression spectra in a non?alcoholic fatty liver disease mouse model induced by a methionine?and choline?deficient diet

日期：2021-10-26 IF：1.73
Life Sciences

Overexpression of microRNA-21-5p prevents the oxidative stress-induced apoptosis of RSC96 cells by suppressing autophagy

日期：2020-11-08 IF：3.708
CELL BIOLOGY INTERNATIONAL

Methylation of miR‐19b‐3p promoter exacerbates inflammatory responses in sepsis‐induced ALI via targeting KLF7

日期：2021-03-24 IF：2.519
Food & Function

Effect of punicalagin on multiple targets in streptozotocin/high-fat diet-induced diabetic mice

日期：2020-12-01 IF：4.372
Journal of Functional Foods

Urolithin A attenuates renal fibrosis by inhibiting TGF-β1/Smad and MAPK signaling pathways

日期：2021-08-23 IF：4.451
frontiers in oncology

Downregulation of miR-181b-5p Inhibits the Viability, Migration, and Glycolysis of Gallbladder Cancer by Upregulating PDHX Under Hypoxia

日期：2021-08-16 IF：6.244
frontiers in oncology

Curcumin in Combination With Omacetaxine Suppress Lymphoma Cell Growth, Migration, Invasion, and Angiogenesis via Inhibition of VEGF/Akt Signaling Pathway

日期：2021-08-11 IF：4.451
Pharmaceutical Biology

Icariin inhibits the expression of IL-1β, IL-6 and TNF-α induced by OGD/R through the IRE1/XBP1s pathway in microglia

日期：2021-10-06 IF：3.503
PHARMAZIE

Effects of different concentrations of metformin on osteoclast differentiation and apoptosis and its mechanism

日期：2021-12-27 IF：1.267
Frontiers in Cardiovascular Medicine

Blockade of Exosome Release Suppresses Atrial Fibrillation by Alleviating Atrial Fibrosis in Canines With Prolonged Atrial Pacing

日期：2021-10-15 IF：6.05
Frontiers in Aging Neuroscience

High-Fat Diet Alleviates Neuroinflammation and Metabolic Disorders of APP/PS1 Mice and the Intervention With Chinese Medicine

日期：2021-10-15 IF：5.75
researchsquare

Role of Exosomal microRNAs and lncRNAs in the Follicular Fluid of Women With Polycystic Ovary Syndrome

日期：2021-07-26 IF：-
Diabetes Metabolic Syndrome and Obesity-Targets and Therapy

Empagliflozin Regulates the AdipoR1/p-AMPK/p-ACC Pathway to Alleviate Lipid Deposition in Diabetic Nephropathy

日期：2021-01-28 IF：3.168
Frontiers in Cardiovascular Medicine

Knockdown of lnc-KCNC3-3:1 Alleviates the Development of Atherosclerosis via Downregulation of JAK1/STAT3 Signaling Pathway

日期：2021-11-03 IF：6.05
Life Sciences

Icariin protects neurons from endoplasmic reticulum stress-induced apoptosis after OGD/R injury via suppressing IRE1α-XBP1 signaling pathway

日期：2020-05-15 IF：5.037
Chemosphere

Maternal exposure to bisphenol A induces fetal growth restriction via upregulating the expression of estrogen receptors.

日期：2021-09-11 IF：7.086
Biomedicine & Pharmacotherapy

JNK downregulation improves olanzapine-induced insulin resistance by suppressing IRS1Ser307 phosphorylation and reducing inflammation

日期：2021-08-17 IF：6.529
hindawi

Vagus Nerve Stimulation Attenuates Hepatic Ischemia/Reperfusion Injury via the Nrf2/HO-1 Pathway

日期：2019-03-28 IF：-
Molecular Medicine Reports

Cinnamaldehyde inhibits psoriasis?like inflammation by suppressing proliferation and inflammatory response of keratinocytes via inhibition of NF?κB and JNK signaling pathways

日期：2021-07-07 IF：2.952
Food & Function

Effect of punicalagin on multiple targets in streptozotocin/high-fat diet-induced diabetic mice

日期：2020-10-20 IF：5.396
Human Cell

MiR-27b-3p inhibits the progression of renal fibrosis via suppressing STAT1

日期：2020-12-14 IF：4.174
frontiers

Inhibition of KCa3.1 Channels Suppresses Atrial Fibrillation via the Attenuation of Macrophage Pro-inflammatory Polarization in a Canine Model With Prolonged Rapid Atrial Pacing

日期：2021-05-31 IF：6.05
International Journal of Molecular Medicine

Knockdown of mesenchymal stem cell?derived exosomal LOC100129516 suppresses the symptoms of atherosclerosis via upregulation of the PPARγ/LXRα/ABCA1 signaling pathway

日期：2021-10-04 IF：4.101
Biomedicine & Pharmacotherapy

Over-expression of Kv4.3 gene reverses cardiac remodeling and transient-outward K+ current (Ito) reduction via CaMKII inhibition in myocardial infarction

日期：2020-11-02 IF：6.529
Helicobacter

Effects of sodium butyrate supplementation on inflammation, gut microbiota, and short-chain fatty acids in Helicobacter pylori-infected mice

日期：2021-02-20 IF：5.753
Journal of Natural Medicines

Bie Jia Jian pill enhances the amelioration of bone mesenchymal stem cells on hepatocellular carcinoma progression

日期：2021-07-23 IF：2.343
Journal of Functional Foods

Anti-renal fibrosis and anti-inflammation effect of urolithin B, ellagitannin-gut microbial-derived metabolites in unilateral ureteral obstruction rats

日期：2021-11-19 IF：4.451
Innate Immunity

MMP9 protects against LPS-induced inflammation in osteoblasts

日期：2019-11-19 IF：2.68
Biology of Reproduction

Par3/integrin β1 regulates embryo adhesion via changing endometrial luminal epithelium polarity

日期：2021-03-02 IF：4.285
Cancer Management and Research

Hypoxic Breast Cancer Cell-Derived Exosomal SNHG1 Promotes Breast Cancer Growth and Angiogenesis via Regulating miR-216b-5p/JAK2 Axis

日期：2022-01-07 IF：3.989
Chemico-Biological Interactions

HDAC6 inhibitor ACY-1215 improves neuropathic pain and its comorbidities in rats of peripheral nerve injury by regulating neuroinflammation

日期：2022-01-05 IF：5.192
Frontiers in Oncology

The Optimal Outcome of Suppressing Ewing Sarcoma Growth in vivo With Biocompatible Bioengineered miR-34a-5p Prodrug

日期：2020-02-15 IF：6.244
Pharmacology

Daphnetin Preconditioning Decreases Cardiac Injury and Susceptibility to Ventricular Arrhythmia following Ischaemia-Reperfusion through the TLR4/MyD88/NF-Κb Signalling Pathway

日期：2021-04-26 IF：2.547
Aging

Knockdown of hsa_circ_0091994 constrains gastric cancer progression by suppressing the miR-324-5p/HMGA1 axis

日期：2021-08-24 IF：5.682
Frontiers in Oncology

Bioinformatics, Molecular Docking and Experiments In Vitro Analyze the Prognostic Value of CXC Chemokines in Breast Cancer

日期：2022-01-14 IF：6.244
research square

Identification of hub genes and pathways in psoriasis through bioinformatics and validation by RT-qPCR

日期：2022-01-14 IF：-
Aging

LncRNA AC136007.2 alleviates cerebral ischemic-reperfusion injury by suppressing autophagy

日期：2021-08-13 IF：5.682
Journal of crohn's and colitis

Mincle/Syk Signalling Promotes Intestinal Mucosal Inflammation Through Induction of Macrophage Pyroptosis in Crohn’s Disease

日期：2020-04-25 IF：-
Cellular and Molecular Neurobiology

Sevoflurane Induces Learning and Memory Impairment in Young Mice Through a Reduction in Neuronal Glucose Transporter 3

日期：2019-12-28 IF：5.046
Research Square

Role and Mechanisms of Probiotics in Regulating the ROS/JNK Signaling Pathway in the Pathogenesis of Nonalcoholic Fatty Liver Disease.

日期：2021-02-04 IF：-
Research Square

Exosomal miR-224-5p from colorectal cancer cells promotes malignant transformation of human colon normal cells by promoting cell proliferation through downregulation of CMTM4

日期：2021-10-05 IF：-
Research Square

Exosomal miR-136-5p Derived From AnlotinibResistant NSCLC Cells Confers Anlotinib Resistance in Non-Small Cell Lung Cancer Through Targeting PPP2R2A

日期：2021-06-17 IF：-
Aging

Curcumol may alleviate psoriasis-like inflammation by inhibiting keratinocyte proliferation and inflammatory gene expression via JAK1/STAT3 signaling

日期：2021-07-27 IF：-
Genomics

Comparative profile of exosomal microRNAs in postmenopausal women with various bone mineral densities by small RNA sequencing

日期：2021-03-27 IF：5.736
JOURNAL OF CELLULAR BIOCHEMISTRY

miR-145 attenuates cardiac fibrosis through the AKT/GSK-3β/β-catenin signaling pathway by directly targeting SOX9 in fibroblasts

日期：2020-10-05 IF：4.429
Aging

CXCL10 and its related key genes as potential biomarkers for psoriasis

日期：2021-09-24 IF：-
Cell Death Discovery

Histone demethylase KDM4D inhibition suppresses renal cancer progression and angiogenesis through JAG1 signaling

日期：2021-10-11 IF：5.241
Research Square

LINC00961 Attenuates TGF-β-induced Endothelialmesenchymal Transition and Myocardial Fibrosis Following Myocardial Infarction

日期：2021-10-20 IF：-
Research Square

miR-145-5p Mimic Inhibits Bone Metastasis of Prostate Cancer Via the Regulation of Epithelial Mesenchymal Transition

日期：2021-07-08 IF：-
Journal of Nanobiotechnology

MiR-144-5p, an exosomal miRNA from bone marrow-derived macrophage in type 2 diabetes, impairs bone fracture healing via targeting Smad1

日期：2021-07-30 IF：10.435
International Journal of Nanomedicine

Mesenchymal Stem Cells Attenuate Renal Fibrosis via Exosomes-Mediated Delivery of microRNA Let-7i-5p Antagomir

日期：2021-05-15 IF：6.4
Biochemical and Biophysical Research Communications

Colchicine prevents ventricular arrhythmias vulnerability in diet-induced obesity rats

日期：2022-04-16 IF：3.575
Bioengineered

Exosomal microRNA-618 derived from mesenchymal stem cells attenuate the progression of hepatic fibrosis by targeting Smad4

日期：2022-02-24 IF：3.269
Adipocyte

The mechanisms underlying olanzapine-induced insulin resistance via the brown adipose tissue and the therapy in rats

日期：2022-01-22 IF：4.534
Cell Death Discovery

Itaconate inhibits ferroptosis of macrophage via Nrf2 pathways against sepsis-induced acute lung injury

日期：2022-02-02 IF：5.241
Aging

Ischemic postconditioning protects nonculprit coronary arteries against ischemia-reperfusion injury via downregulating miR-92a, miR-328 and miR-494

日期：2022-03-23 IF：5.682
Marine Drugs

Novel Prenylated Indole Alkaloids with Neuroprotection on SH-SY5Y Cells against Oxidative Stress Targeting Keap1–Nrf2

日期：2022-03-04 IF：5.118
CHINESE JOURNAL OF CHEMISTRY

Undescribed Meroterpenoids from Hypericum japonicum with Neuroprotective Effects on H2O2 Insult SH‐SY5Y Cells Targeting Keap1‐Nrf2

日期：2022-02-24 IF：6
Small

Cell-Free Extracts from Human Fat Tissue with a Hyaluronan-Based Hydrogel Attenuate Inflammation in a Spinal Cord Injury Model through M2 Microglia/Microphage Polarization

日期：2022-03-25 IF：13.281
Bioengineered

Exosomes from miR-374a-5p-modified mesenchymal stem cells inhibit the progression of renal fibrosis by regulating MAPK6/MK5/YAP axis

日期：2022-02-09 IF：3.269
CANCER BIOLOGY & THERAPY

MiR-376a-3p increases cell apoptosis in acute myeloid leukemia by targeting MT1X

日期：2022-04-21 IF：4.742
Frontiers in Physiology

Blocking Intermediate-Conductance Calcium-Activated Potassium Channels in the Macrophages Around Ganglionated Plexi Suppresses Atrial Fibrillation Vulnerability in Canines With Rapid Atrial Pacing

日期：2022-04-01 IF：4.566
Research Square

Role of Global Longitude Strain related miRNAs as potential prognostic indicators in myocardial infarction

日期：2022-01-18 IF：-
Cancer Management and Research

Hypoxic Breast Cancer Cell-Derived Exosomal SNHG1 Promotes Breast Cancer Growth and Angiogenesis via Regulating miR-216b-5p/JAK2 Axis

日期：2022-01-07 IF：3.989
Chinese Journal of Tissue Engineering Research

Preventive and therapeutic effects of naringin on experimental autoimmune encephalomyelitis via regulating microglial polarization

日期：2022-03-08 IF：-
口腔疾病防治

LED紅光對(duì)人根尖乳頭干細(xì)胞增殖和成骨分化的影響

日期：2021-12-10 IF：-
CELL BIOLOGY INTERNATIONAL

Methylation of miR-19b-3p promoter exacerbates inflammatory responses in sepsis-induced ALI via targeting KLF7

日期：2021-03-24 IF：3.612
Biochemical and Biophysical Research Communications

Exosomal long non-coding RNA LIPCAR derived from oxLDL-treated THP-1 cells regulates the proliferation of human umbilical vein endothelial cells and human vascular smooth muscle cells

日期：2021-08-26 IF：3.575
Frontiers in Cell and Developmental Biology

Comprehensive Analysis of the Prognostic Significance of Hsa-miR-100-5p and Its Related Gene Signature in Stomach Adenocarcinoma

日期：2021-09-17 IF：6.684
Frontiers in Pharmacology

Fusobacterium nucleatumCorrigendum: Activates Endoplasmic Reticulum Stress to Promote Crohn's Disease Development via the Upregulation of CARD3 Expression.

日期：2021-05-19 IF：5.81
Journal of Cardiovascular Pharmacology

Metformin Attenuates Hypoxia-induced Endothelial Cell Injury by Activating the AMP-Activated Protein Kinase Pathway

日期：2021-06-01 IF：3.105
BioMed Research International

Propranolol Suppresses Proliferation and Migration of HUVECs through Regulation of the miR-206/VEGFA Axis

日期：2021-10-16 IF：3.411
天津醫(yī)藥

The effect of atorvastatin calcium on pulmonary vascular remodeling in chronic obstructive pulmonary disease rats

日期：2021-02-04 IF：-
Journal of Clinical Images and Medical Case Reports

Role of global longitude strain related miRNAs as potential prognostic indicators in myocardial infarction

日期：2022-01-24 IF：-
Journal of Oncology

Overexpressed lncRNA LINC00893 Suppresses Progression of Colon Cancer by Binding with miR-146b-3p to Upregulate PRSS8

日期：2022-05-05 IF：4.375
Research Square

Role of Global Longitude Strain related miRNAs as potential prognostic indicators in myocardial infarction

日期：2022-01-18 IF：-
Disease Markers

Role of Cardiomyocyte-Derived Exosomal MicroRNA-146a-5p in Macrophage Polarization and Activation

日期：2022-05-02 IF：3.434
CHINESE JOURNAL OF CHEMISTRY

Undescribed Meroterpenoids from Hypericum japonicum with Neuroprotective Effects on H2O2 Insult SH-SY5Y Cells Targeting Keap1-Nrf2

日期：2022-02-24 IF：6
Bioengineered

Knockdown of lncRNA PCAT6 suppresses the growth of non-small cell lung cancer cells by inhibiting macrophages M2 polarization via miR-326/KLF1 axis

日期：2022-05-24 IF：3.269
HEREDITAS

Identification of key apoptosis-related genes and immune infiltration in the pathogenesis of psoriasis

日期：2022-06-22 IF：3.271
Journal of Biobased Materials and Bioenergy

Liquid Chromatography-Mass Spectrometry Characterized Hydrolysate Fractions Possess Anticancer Activity In Vitro

日期：2022-02-22 IF：0.708
Small

Cell-Free Extracts from Human Fat Tissue with a Hyaluronan-Based Hydrogel Attenuate Inflammation in a Spinal Cord Injury Model through M2 Microglia/Microphage Polarization

日期：2022-03-25 IF：15.153
Gene

Identification of immunity- and ferroptosis-related genes for predicting the prognosis of serous ovarian cancer

日期：2022-07-02 IF：3.913
Oxidative Medicine and Cellular Longevity

Exosomal miR-224-5p from Colorectal Cancer Cells Promotes Malignant Transformation of Human Normal Colon Epithelial Cells by Promoting Cell Proliferation through Downregulation of CMTM4

日期：2022-06-30 IF：7.31
Oncology Letters

Connexin 43 overexpression induces lung cancer angiogenesis in vitro following phosphorylation at Ser279 in its C?terminus

日期：2022-07-05 IF：3.111
JOURNAL OF NANOBIOTECHNOLOGY

MiR-21 regulating PVT1/PTEN/IL-17 axis towards the treatment of infectious diabetic wound healing by modified GO-derived biomaterial in mouse models

日期：2022-06-28 IF：9.429
Molecular Medicine Reports

LncRNA LINC00961 regulates endothelial?mesenchymal transition via the PTEN?PI3K?AKT pathway

日期：2022-06-02 IF：3.423
Tianjin Medical Journal

依達(dá)拉奉右莰醇通過抑制TLR4/NF-κB信號(hào)通路減輕實(shí)驗(yàn)性自身免疫性腦脊髓炎小鼠炎癥反應(yīng)

日期：2022-05-18 IF：-
INFLAMMATION RESEARCH

Knockdown of lncRNA H19 alleviates ox-LDL-induced HCAECs inflammation and injury by mediating miR-20a-5p/HDAC4 axis

日期：2022-07-19 IF：6.986
Computational and Mathematical Methods in Medicine

Long Noncoding RNA Zinc Finger Antisense 1 Affects Glucocorticoid-Induced Osteonecrosis of the Femoral Head by Performing as a ceRNA for MicroRNA-124-3p and Accelerating Transforming Growth Factor Type III Receptor

日期：2022-07-18 IF：2.809
Frontiers in Immunology

Characterization of Immune-Related Molecular Subtypes and a Prognostic Signature Correlating With the Response to Immunotherapy in Patients With Gastric Cancer

日期：2022-08-01 IF：8.786
Frontiers in Immunology

Characterization of Immune-Related Molecular Subtypes and a Prognostic Signature Correlating With the Response to Immunotherapy in Patients With Gastric Cancer

日期：2022-07-08 IF：8.786
Computational and Mathematical Methods in Medicine

Long Noncoding RNA Zinc Finger Antisense 1 Affects Glucocorticoid-Induced Osteonecrosis of the Femoral Head by Performing as a ceRNA for MicroRNA-124-3p and Accelerating Transforming Growth Factor Type III Receptor

日期：2022-07-18 IF：2.809
Frontiers in Oncology

iRGD-modified exosomes-delivered BCL6 siRNA inhibit the progression of diffuse large B-cell lymphoma

日期：2022-08-02 IF：5.738
Scientific Reports

Vagus Nerve Stimulation Attenuates Acute Kidney Injury Induced by Hepatic Ischemia/Reperfusion Injury by Suppressing Inflammation, Oxidative Stress, and Apoptosis in Rats

日期：2022-08-17 IF：4.996
DRUG DEVELOPMENT RESEARCH

Tetrahydropalmatine induces the polarization of M1 macrophages to M2 to relieve limb ischemia-reperfusion-induced lung injury via inhibiting the TLR4/NF-κB/NLRP3 signaling pathway

日期：2022-08-17 IF：5.004
天津醫(yī)藥

黃芩素對(duì)實(shí)驗(yàn)性自身免疫性腦脊髓炎小鼠的影響及機(jī)制研究

日期：2022-04-15 IF：-
Journal of Clinical Images and Medical Case Reports

Role of global longitude strain related miRNAs as potential prognostic indicators in myocardial infarction

日期：2022-01-24 IF：-
Disease Markers

Combined Transcriptomic and Metabolomic Analysis of Women with Polycystic Ovary Syndrome

日期：2022-08-28 IF：3.434
European Journal of Histochemistry

Long non-coding RNA WAC antisense RNA 1 mediates hepatitis B virus replication in vitro by reinforcing miR-192-5p/ATG7-induced autophagy

日期：2022-09-02 IF：1.966
Journal of Functional Foods

Urolithin A attenuates renal fibrosis by inhibiting TGF-β1/Smad and MAPK signaling pathways

日期：2021-05-08 IF：4.451
CELL BIOLOGY INTERNATIONAL

Methylation of miR‐19b‐3p promoter exacerbates inflammatory responses in sepsis‐induced ALI via targeting KLF7

日期：2021-03-24 IF：3.612
Frontiers in Oncology

microRNA-145-5p inhibits prostate cancer bone metastatic by modulating the epithelial-mesenchymal transition

日期：2022-09-06 IF：5.738
Molecules

Effect of Nanoparticles of DOX and miR-125b on DNA Damage Repair in Glioma U251 Cells and Underlying Mechanisms

日期：2022-09-07 IF：4.927
European Journal of Histochemistry

Polydatin reverses oxidation low lipoprotein (oxLDL)-induced apoptosis of human umbilical vein endothelial cells via regulating the miR-26a-5p/BID axis

日期：2022-09-02 IF：1.966
Chinese Journal of Tissue Engineering Research

Mechanism by which naringin regulates osteogenic differentiation in osteoblasts

日期：2022-06-11 IF：-
Frontiers in Cardiovascular Medicine

LINC00452 overexpression reverses oxLDL-induced injury of human umbilical vein endothelial cells (HUVECs) via regulating miR-194-5p/IGF1R axis

日期：2022-09-09 IF：5.846
International Journal of Biological Macromolecules

HIF1α lactylation enhances KIAA1199 transcription to promote angiogenesis and vasculogenic mimicry in prostate cancer

日期：2022-10-06 IF：8.025
Drug Development Research

Knockdown of IGF2BP3 inhibits the tumorigenesis of gallbladder cancer and modifies tumor microenvironment

日期：2022-10-02 IF：5.004
European Journal of Histochemistry

VEGF promotes diabetic retinopathy by upregulating the PKC/ET/NF-κB/ICAM-1 signaling pathway

日期：2022-10-27 IF：1.966
International Immunopharmacology

Maresin1 ameliorates ventricular remodelling and arrhythmia in mice models of myocardial infarction via NRF2/HO-1 and TLR4/NF-kB signalling

日期：2022-10-21 IF：5.714
European Journal of Histochemistry

Docetaxel-resistant triple-negative breast cancer cell-derived exosomal lncRNALINC00667 reduces the chemosensitivity of breast cancer cells to docetaxel viatargeting miR-200b-3p/Bcl-2 axis

日期：2022-10-25 IF：1.966
Drug Design Development and Therapy

Exosomes Derived from Hypoxic Glioma Cells Reduce the Sensitivity of Glioma Cells to Temozolomide Through Carrying miR-106a-5p

日期：2022-10-13 IF：4.319
Scientific Reports

Vagus nerve stimulation attenuates acute kidney injury induced by hepatic ischemia/reperfusion injury in rats

日期：2022-12-15 IF：4.996
Frontiers in Cellular and Infection Microbiology

New insights of necroptosis and immune infiltration in sepsis-induced myocardial dysfunction from bioinformatics analysis through RNA-seq in mice

日期：2022-12-15 IF：6.073
European Journal of Histochemistry

Combination of tolvaptan and valsartan improves cardiac and renal functions in doxorubicin-induced heart failure in mice

日期：2022-11-11 IF：1.966
BMC Medicine

Prolonged anesthesia induces neuroinflammation and complement-mediated microglial synaptic elimination involved in neurocognitive dysfunction and anxiety-like behaviors

日期：2023-01-05 IF：11.15
International Journal of Nanomedicine

Exosomal miR-133a-3p Derived from BMSCs Alleviates Cerebral Ischemia-Reperfusion Injury via Targeting DAPK2

日期：2023-01-05 IF：7.033
Oxidative Medicine and Cellular Longevity

Sulforaphane Delays Intervertebral Disc Degeneration by Alleviating Endoplasmic Reticulum Stress in Nucleus Pulposus Cells via Activating Nrf-2/HO-1

日期：2023-01-07 IF：7.31
Journal of Ankara University School of Medicine

Magnolia Officinalis Ekstrakt?n?n Kardiyak Ya?lanmada G?zlenen Mitokondri Fonksiyon Bozuklu?u üzerindeki Düzenleyici Etkileri

日期：2022-11-25 IF：-
Drug Design Development and Therapy

Exosomes Derived from Hypoxic Glioma Cells Reduce the Sensitivity of Glioma Cells to Temozolomide Through Carrying miR-106a-5p

日期：2022-12-14 IF：4.319
CELL BIOLOGY INTERNATIONAL

Targeting of MAD2L1 by miR-515-5p involves the regulation of cell cycle arrest and apoptosis of colorectal cancer cells

日期：2022-02-10 IF：4.473
CELL BIOLOGY INTERNATIONAL

Targeting of MAD2L1 by miR-515-5p involves the regulation of cell cycle arrest and apoptosis of colorectal cancer cells

日期：2022-02-10 IF：4.473
Biomaterials Research

Engineered exosomes enriched in netrin-1 modRNA promote axonal growth in spinal cord injury by attenuating inflammation and pyroptosis

日期：2023-01-17 IF：15.863
bioRxiv

Exosomes derived from BMSCs with miR-124-3p inhibitor protects against LPS-induced endometritis through regulation of DUSP6, p-p65 and p-ERK

日期：2023-02-02 IF：
CNS Neuroscience & Therapeutics

Exosomal miR-128-3p reversed fibrinogen-mediated inhibition of oligodendrocyte progenitor cell differentiation and remyelination after cerebral ischemia

日期：2023-02-08 IF：7.035
Cell Biology and Toxicology

The method of sinus node?like pacemaker cells from human induced pluripotent stem cells by BMP and Wnt signaling

日期：2023-02-15 IF：6.819
Cell Biology and Toxicology

The method of sinus node-like pacemaker cells from human induced pluripotent stem cells by BMP and Wnt signaling

日期：2023-02-15 IF：6.1
Current Molecular Medicine

Study on the Mechanism of Estrogen Regulating Endometrial Fibrosis After Mechanical Injury Via MIR-21-5P/PPARΑ/FAO Axis

日期：2023-02-28 IF：2.5
Cancer Gene Therapy

Loss of exosomal miR-200b-3p from hypoxia cancer-associated fibroblasts promotes tumorigenesis and reduces sensitivity to 5-Flourouracil in colorectal cancer via upregulation of ZEB1 and E2F3

日期：2023-03-08 IF：5.85
Reproductive Biology

circPLOD2 knockdown suppresses endometriosis progression via the miR-216a-5p/ZEB1 axis

日期：2023-03-12 IF：2.09
CNS Neuroscience & Therapeutics

Dihydroorotate dehydrogenase regulates ferroptosis in neurons after spinal cord injury via the P53-ALOX15 signaling pathway

日期：2023-03-22 IF：7.035
ACS Chemical Neuroscience

Inhibition of PINK1-Mediated Mitophagy Contributes to Postoperative Cognitive Dysfunction through Activation of Caspase-3/GSDME-Dependent Pyroptosis

日期：2023-02-22 IF：5.78
Functional & Integrative Genomics

Astragaloside IV suppresses the migration and EMT progression of cervical cancer cells by inhibiting macrophage M2 polarization through TGFβ/Smad2/3 signaling

日期：2024-04-21 IF：3.67
ndian Journal of Experimental Biology

Antiproliferative, anti-inflammatory, antitumoral and proapoptotic effects of calcitriol on MCF-7 and MCF-10A cell lines

日期：2023-05-01 IF：0.944
Experimental Neurology

Exosomal miR-23b-3p from bone mesenchymal stem cells alleviates experimental autoimmune encephalomyelitis by inhibiting microglial pyroptosis

日期：2023-05-01 IF：5.62
Open Medicine

circRNA THBS1 silencing inhibits the malignant biological behavior of cervical cancer cells via the regulation of miR-543/HMGB2 axis

日期：2023-05-07 IF：2.1
International Immunopharmacology

Nesfatin-1, a novel energy-regulating peptide, alleviates pulmonary fibrosis by blocking TGF-β1/Smad pathway in an AMPKα-dependent manner

日期：2023-05-18 IF：5.714
Biomedicine & Pharmacotherapy

Mesenchymal stem cell-derived exosomal microRNA-367–3p alleviates experimental autoimmune encephalomyelitis via inhibition of microglial ferroptosis by targeting EZH2

日期：2024-02-23 IF：7.419
Food and Chemical Toxicology

Soluble thrombomodulin alleviates Diquat-induced acute kidney injury by inhibiting the HMGB1/IκBα/NF-κB signalling pathway

日期：2023-06-03 IF：5.572
BMC Pulmonary Medicine

The role of rhIGF-1/BP3 in the prevention of pulmonary hypertension in bronchopulmonary dysplasia and its underlying mechanism

日期：2023-06-15 IF：3.1
Immunity, Inflammation and Disease

Death receptor 3 is involved in preeclampsia through regulating placental trophoblast cell physiology by inactivating the PI3K/AKT pathway

日期：2023-09-27 IF：3.2
Revista Brasileira de Farmacognosia-Brazilian Journal of Pharmacognosy

Panax notoginseng Saponins Play a Protective Role in Acute Cerebral Infarction by Regulating lncRNA SNHG15

日期：2023-11-11 IF：1.6
Environmental Toxicology

Cuproptosis-related lncRNAs ovarian cancer: Multi-omics analysis of molecular mechanisms and potential therapeutic targets

日期：2023-11-29 IF：4.5
European Review for Medical and Pharmacological Sciences

Roxadustat protects rat renal tubular epithelial cells from hypoxia-induced injury through the TGF-β1/Smad3 signaling pathway

日期：2023-12-01 IF：3.3
Life Science Alliance

tRF-1:30-Gly-CCC-3 inhibits thyroid cancer via binding to PC and modulating metabolic reprogramming

日期：2023-12-11 IF：4.4
Revista Brasileira de Farmacognosia

Effects of Liquiritin on Mitochondrial Dynamics in Cerebral Ischemia–Reperfusion Injury by Regulating Nurr1 via the YAP-INF2-Mitochondrial Fission Pathway

日期：2023-12-28 IF：1.6
Biochemical and Biophysical Research Communications

SIRT1 overexpression by melatonin and resveratrol combined treatment attenuates premature ovarian failure through activation of SIRT1/FOXO3a/BCL2 pathway

日期：2024-02-28 IF：3.1
EUROPACE

Ubiquitin-specific protease 38 promotes inflammatory atrial fibrillation induced by pressure overload

日期：2024-01-29 IF：6.1
Long noncoding RNA XIST inhibition promotes Leydig cell apoptosis by acting as a competing endogenous RNA for microRNA-145a-5p that targets SIRT1 in late-onset hypogonadism

Cell and Tissue Research

日期：2024-02-14 IF：6.8
Effects of KLF11 on Vascular Smooth Muscle Cells and its Underlying Mechanisms in Intracranial Aneurysm

Biochemical Genetics

日期：2024-02-18 IF：5.4
Extracellular vesicles containing anti-miR-128-3p derived from mesenchymal stem cells attenuate cerebral ischemia-reperfusion injury by suppressing neuronal pyroptosis and modulating microglia polariz

Research Article

日期：2024-02-21 IF：6.2
β-catenin Activation Reprograms Ammonia Metabolism to Promote Senescence Resistance in Hepatocellular Carcinoma

Cancer Research

日期：2024-02-28 IF：9.3
Research Article

Extracellular vesicles containing anti-miR-128-3p derived from mesenchymal stem cells attenuate cerebral ischemia-reperfusion injury by suppressing neuronal pyroptosis and modulating microglia polarization

日期：2024-02-21 IF：6.2
Cancer Research

β-catenin Activation Reprograms Ammonia Metabolism to Promote Senescence Resistance in Hepatocellular Carcinoma

日期：2024-02-28 IF：9.3
Journal of Orthopaedic Surgery and Research

Inhibition of cc chemokine receptor 10 ameliorates osteoarthritis via inhibition of the phosphoinositide-3-kinase/Akt/mammalian target of rapamycin pathway

日期：2024-03-01 IF：5.6
Poultry Science

Melatonin alleviates endoplasmic reticulum stress and follicular granulosa cell apoptosis by regulating ATF4 to activate mTOR signaling pathway in chickens

日期：2024-03-15 IF：7.6
Cytotechnology

PABPC1 silencing inhibits pancreatic cancer cell proliferation and EMT, and induces apoptosis via PI3K/AKT pathway

日期：2024-04-22 IF：2.2
Advanced Healthcare Materials

ROS-Responsive Injectable Hydrogel Loaded with SLC7A11-modRNA Inhibits Ferroptosis and Mitigates Intervertebral Disc Degeneration in Rats

日期：2024-05-01 IF：10
Open Medicine

ANO6 (TMEM16F) inhibits gastrointestinal stromal tumor growth and induces ferroptosis

日期：2024-05-15 IF：2.1
Cancer Letters

Preoperative neoadjuvant targeted therapy remodels intra-tumoral heterogeneity of clear-cell renal cell carcinoma and ferroptosis inhibition induces resistance progression

日期：2024-05-18 IF：9.6
Biochemical Pharmacology

miR-486-5p-rich extracellular vesicles derived from patients with olanzapine-induced insulin resistance negatively affect glucose-regulating function

日期：2024-05-22 IF：5.8
Aging Cell

HIF-1α-induced expression of the m6A reader YTHDF1 inhibits the ferroptosis of nucleus pulposus cells by promoting SLC7A11 translation

日期：2024-05-23 IF：7.8
BOLETIN LATINOAMERICANO Y DEL CARIBE DE PLANTAS MEDICINALES Y AROMáTICAS

Posibilidad de inducción de apoptósis y necrosis en células cancerosas mediante Clinopodium vulgare L. y ácidos fenólicos, y detección de flavonoides mediante LC-MS-MS

日期：2024-05-26 IF：0.9
JOURNAL OF PERIODONTAL RESEARCH

Low-energy red light-emitting diode irradiation enhances osteogenic differentiation of periodontal ligament stem cells by regulating miR-146a-5p

日期：2024-06-06 IF：3.4
BMC BIOINFORMATICS

Identification and validation of the shared signature gene MMP9 and ANGPTL4 and its regulatory mechanisms in Type 2 Diabetes combined with Osteoarthritis

日期：2024-06-07 IF：3
Heliyon

Atrial fibroblast-derived exosomal miR-21 upregulate myocardial KCa3.1 via the PI3K-Akt pathway during rapid pacing

日期：2024-06-14 IF：3.4
Biochemical Genetics

Exosomal miR-17-92 Cluster from BMSCs Alleviates Apoptosis and Inflammation in Spinal Cord Injury

日期：2024-07-03 IF：2.1
Brain and Behavior

The antidepressant effect of Shexiang Baoxin Pills on myocardial infarction rats with depression may be achieved through the inhibition of the NLRP3 inflammasome pathway

日期：2024-07-05 IF：2.6
FASEB JOURNAL

Enhancing high-quality fat survival: A novel strategy using cell-free fat extract

日期：2024-07-12 IF：4
PLoS One

Key extracellular proteins and TF-miRNA co-regulatory network in diabetic foot ulcer: Bioinformatics and experimental insights

日期：2024-08-12 IF：2.9
Journal of Investigative Surgery

Role of SFRP5 in Non-Small Cell Lung Cancer and Its Correlation with SUV of 18F-FDG PET-CT

日期：2024-07-29 IF：2.1
Revista Brasileira de Farmacognosia-Brazilian Journal of Pharmacognosy

Shionone Exhibits Anti-inflammatory and Antiproliferative Effects in Pulmonary Arterial Endothelial Cells and Smooth Muscle Cells via SIRT1 in Pulmonary Arterial Hypertension

日期：2024-07-29 IF：1.4
Frontiers in Immunology

Unveiling the bioinformatic genes and their involved regulatory mechanisms in type 2 diabetes combined with osteoarthritis

日期：2024-08-08 IF：5.7
DNA and Cell Biology

Bone Marrow Mesenchymal Stem Cells–Derived Extracellular Vesicle miR-208a-3p Alleviating Spinal Cord Injury via Regulating the Biological Function of Spinal Cord Neurons

日期：2024-08-12 IF：2.6
JOURNAL OF PHARMACY AND PHARMACOLOGY

Mesenchymal stem cell-derived exosomal microRNA-367-3p mitigates lower limb ischemia/reperfusion injury in mouse skeletal muscle via EZH2 targeting

日期：2024-08-13 IF：2.8
Molecular Pharmaceutics

Insulin-Induced Gene 1-Enhance Secretion of BMSC Exosome Enriched in miR-132–3p Promoting Wound Healing in Diabetic Mice

日期：2024-08-13 IF：4.5
International Immunopharmacology

Epimedii Folium decoction ameliorates osteoporosis in mice through NLRP3/caspase-1/IL-1β signalling pathway and gut-bone axis

日期：2024-08-20 IF：4.8
Functional & Integrative Genomics

Astragaloside IV suppresses the migration and EMT progression of cervical cancer cells by inhibiting macrophage M2 polarization through TGFβ/Smad2/3 signaling

日期：2023-04-21 IF：3.67
European Journal of Histochemistry

Tumor cells-derived exosomal PD-L1 promotes the growth and invasion of lung cancer cells in vitro via mediating macrophages M2 polarization

日期：2023-08-01 IF：2
CELL BIOCHEMISTRY AND BIOPHYSICS

TREM2 Impairs Glycolysis to Interrupt Microglial M1 Polarization and Inflammation via JAK2/STAT3 Axis

日期：2024-09-06 IF：1.8
Revista Brasileira de Farmacognosia

Icariside II Suppresses the Malignant Behaviors of Breast Cancer Cells by Inhibiting PTGES3 Expression

日期：2024-08-30 IF：1.4
BMC Oral Health

Effects of Porphyromonas gingivalis lipopolysaccharide on the behavior of human dental pulp stem cells in vitro and their inflammation-related transcriptomics profile

日期：2024-08-20 IF：2.6
預(yù)印本

The RNA m5C methylase NSUN4 protects retinal ganglion cells by regulating m5C methylation in the Hedgehog signaling pathway

日期：2024-09-10 IF：0
BOLETIN LATINOAMERICANO Y DEL CARIBE DE PLANTAS MEDICINALES Y AROMáTICAS

Possible induction of apoptotic and necrotic death pathways in lung cancer cells by Clinopodium vulgareL. and phenolic acids and flavonoids detection by LC-MS-MS

日期：2024-05-26 IF：0.7
Journal of Nanobiotechnology

Chondrocyte-targeted exosome-mediated delivery of Nrf2 alleviates cartilaginous endplate degeneration by modulating mitochondrial fission

日期：2024-05-26 IF：10.6
Biochemical Genetics

Effects of KLF11 on Vascular Smooth Muscle Cells and its Underlying Mechanisms in Intracranial Aneurysm

日期：2024-02-18 IF：2.4
Scientific Reports

Comprehensive analyses of solute carrier family members identify SLC12A2 as a novel therapy target for colorectal cancer

日期：2024-02-23 IF：4.6
Research Article

Pretreatment of GPER agonist G1 protects male mice from septic-induced cardiomyopathy via increasing mitochondria fusion against dysregulated linoleic acid / arachidonic acid metabolism

日期：2024-04-16 IF：0
Open Medicine

ANO6?(TMEM16F) inhibits gastrointestinal stromal tumor growth and induces ferroptosis

日期：2024-05-15 IF：2.1
CELL BIOCHEMISTRY AND BIOPHYSICS

TREM2 Impairs Glycolysis to Interrupt Microglial M1 Polarization and Inflammation via JAK2/STAT3 Axis

日期：2024-09-06 IF：1.8
Food Science and Human Wellness

Hypoglycemic effect and the mechanism of action of a polysaccharide from sweet corncob in a high-fat diet and streptozotocin-induced diabetic mice

日期：2024-05-13 IF：5.6
Skin Research and Technology

Proanthocyanidins alleviate Henoch-Sch?nlein purpura by mitigating inflammation and oxidative stress through regulation of the TLR4/MyD88/NF-κB pathway

日期：2024-09-10 IF：2
scientific reports

Discussion of spinal cord neurons apoptosis and neuroprotection mechanism of NGF gene transfection mediated by recombinant adenovirus in EAE mice

日期：2024-09-12 IF：3.8
Stem Cell Research & Therapy

BMSC-Exo miR-122-5p facilitates osteogenic differentiation of MC3T3-E1 cells through specifically suppressing SPRY2

日期：2024-09-13 IF：7.1
Genes & Genomics

Roles and action mechanisms of NRIP1 in pre-eclampsia

日期：2024-09-13 IF：1.6
Molecular Biology Reports

Poricoic acid a ameliorates high glucose-induced podocyte injury by regulating the AMPKα/FUNDC1 pathway

日期：2024-09-21 IF：2.6

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