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            Recombinant Human BCMA (C-Fc)
            EPT174
            規(guī)格: 價(jià)格:
            50μg ¥2640.00

            Overview

            Product name: Recombinant Human BCMA (C-Fc)
            Description: Recombinant Human B-cell Maturation Protein is produced by our Mammalian expression system and the target gene encoding Met1-Ala54 is expressed with a Fc tag at the C-terminus.
            Accession: Q02223
            Molecular weight: 32.8 KDa
            Apparent molecular weight: 38-40 KDa, reducing conditions
            Purity: Greater than 95% as determined by reducing SDS-PAGE.
            Endotoxin: Less than 0.1 ng/μg (1 EU/μg) as determined by LAL test.
            Biological activity: Loaded Mouse BAFF-mFc(Cat#C06U) on AMC Biosensor, can bind Human BCMA-Fc(Cat#CS79) with an affinity constant of 0.44 nM as determined in BLI assay.?
            Redissolve: Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.?
            Storage: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
            Delivery condition: The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below.
            Background: B cell maturation protein (BCMA) is a type III membrane protein which belongs to the TNF receptor superfamily (TNFRSF17). BCMA contains one extracellular cysteine rich domain, as well as TACI. Human BCMA is a 184 amino acid (aa) protein consisting of a 54 aa extracellular domain, a 23 aa transmembrane domain, and a 107 aa intracellular domain. Mouse and human BCMA share 62% amino acid identity. BCMA is mainly expressed in immune organs and mature B cell lines. BCMA appears to be localized to the Golgi compartment. BCMA may play an important role in B cell development, function and regulation.
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